By Elaine S. Jaffe M.D., Raul C. Braylan M.D., Koji Nanba M.D. (auth.), Joseph Aisner M.D., Paul Chang M.D. (eds.)
In fresh years the sector of melanoma therapy has been burgeoning with ever increasing curiosity and commitments to investigate and remedy. along with the big variety of uniqueness journals and guides dedicated to melanoma similar fields, approximately each basic clinical magazine includes a number of articles relating to melanoma therapy and learn. one other instance of this increasing dedication and curiosity is mirrored within the inner drugs subspecialty of scientific Oncology which, for the reason that its acceptance as a subspecialty in 1973, has develop into the second one so much populated subspecialty, moment in simple terms to cardiology. This burgeoning curiosity and dedication is clearly acceptable in view of the superiority and prevalence of many of the cancers. those illnesses represent, in the end, one of the most vital and devastating difficulties of civilized guy. it's been really pleasant to these concerned with melanoma examine and treatment to watch the expanding curiosity in those illnesses being translated into genuine advancements in sufferer care - advancements in size of survival, advancements in caliber of survival, and enhancements in palliative care. One want purely examine Hodgkin's sickness to watch the excessive fee of medication now generally acquired while, some time past, many sufferers' sickness persevered to development with deadly outcomes. a few of these advancements took place via greater staging concepts, and different advancements, as could be mentioned within the bankruptcy on Hodgkin's, happened from the applying of early chemotherapy. additional examine in Hodgkin's sickness continues to be happening which will enhance effects and reduce remedy comparable complications.
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Other extranodal areas include bone, skin, breast, testes, central nervous system, head and neck, or lung. 24 25 Some patients found to have a malignant lymphoma will present with constitutional or systemic symptoms as the only manifestation of disease or with both symptoms and lymphadenopathy. These include an unexplained fever of 380 C or night sweats, or weight loss of greater than 10% of normal body weight. Approximately 10% of patients with a non-Hodgkin's lymphoma will have one or more of these symptoms at the time of diagnosis, and these patients have a poorer prognosis than those who are asymptomatic (2).
Jones, EE, Z Fuks, M Bull, et aI, Non-Hodgkin's lymphomas. IV Clinico- 11. Lukes, RJ and RD Collins, Immunologic characterization of human 12. Lennert, K, H Stein and E Kaiserling, Cytological and functional criteria understanding of morphologic diversity. Am J Pathol 94:103-192, 1979. pathologic correlation in 405 cases. Cancer 31:806-823, 1973 malignant lymphomas. Cancer 34:1488-1503, 1974 for the classification of malignant lymphomata. Brit J Cancer 31 Supp 11:29-43, 1975 13. Fu, SM, RJ Winchester, T Feizi, et aI, Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone marrow derived lymphocytes.
July 23-29, 1978, Paris, France 54. Jaffe, ES, TP Keneklis, JA Donlon, et al. (manuscript in preparation) ST AGING AND TREATMENT OF NON-HODGKIN'S LYMPHOMAS Charles H. Diggs Baltimore Cancer Research Program of the Division of Cancer Treatment, National Cancer Institute at the University of Maryland Hospital, Baltimore, Maryland ST AGING OF NON-HODGKIN'S LYMPHOMAS Introduction The non-Hodgkin's lymphomas are a somewhat heterogeneous group of diseases as can be seen from the previous article on their pathologic characteristics.
Cancer Treatment Research by Elaine S. Jaffe M.D., Raul C. Braylan M.D., Koji Nanba M.D. (auth.), Joseph Aisner M.D., Paul Chang M.D. (eds.)